Corpus callosum in schizophrenia with deficit and non-deficit syndrome:a statistical shape analysis
作者机构：Department of RadiologyMedical Faculty of Bülent Ecevit UniversityKozluZonguldakTurkey Department of BiostatisticsBursa Uludag University Faculty of MedicineBursaTurkey Department of RadiologyBursa Uludag University Faculty of MedicineBursaTurkey Department of PsychiatryÇorlu State HospitalÇorluTurkey Department of PsychiatryMedical Faculty of Tekirdag Namık Kemal UniversityTekirdagTurkey
出 版 物：《General Psychiatry》 (综合精神医学（英文）)
年 卷 期：2021年第34卷第6期
页 面：42-48页
核心收录：
学科分类：1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学]
主 题：schizophrenia shape analysis
摘 要：Background The corpus callosum(CC)is the most targeted region in the cerebrum that integrates cognitive data between homologous areas in the right and left *** Our study used statistical analysis to determine whether there was a correlation between shape changes in the CC in patients with schizophrenia(SZ)(deficit syndrome(DS)and non-deficit syndrome(NDS))and healthy control(HC)*** This study consisted of 27 HC subjects and 50 schizophrenic patients(20 with DS and 30 with NDS).3 patients with DS and 4 patients with NDS were ***-dimensional,sagittal,T1-spoiled,gradient-echo imaging was *** anatomical landmarks were selected and marked on each image using specific *** As to comparing the Procrustes mean shapes of the CC,statistically significant differences were observed between HC and SZ(DS+NDS)(p=0.017,James’s Fj=73.732),HC and DS(p0.001,James’s Fj=140.843),HC and NDS(p=0.006,James’s Fj=89.178)and also DS and NDS(p0.001,James’s Fj=152.967).Shape variability in the form of CC was 0.131,0.085,0.082 and 0.086 in the HC,SZ(DS+NDS),DS and NDS groups,*** This study reveals callosal shape variations in patients with SZ and their DS and NDS subgroups that take into account the CC’s topographic distribution.
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