Chronic colchicine poisoning with neuromyopathy,gastric ulcers and myelosuppression in a gout patient:A case report
作者机构：Department of EmergencyQingdao Central HospitalThe Second Affiliated Hospital of Qingdao University Medical CollegeQingdao 266042Shandong ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2021年第9卷第35期
页 面：11050-11055页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Colchicine poisoning Neuromyopathy Myelosuppression Gastric ulcer Gout Case report
摘 要：Colchicine has been widely used as an anti-gout medication over the past ***,it is less commonly used due to its narrow therapeutic range,meaning that its lethal dose is close to its therapeutic *** lethal dose of colchicine is considered to be 0.8 mg/*** chronic colchicine poisoning has multiple manifestations,it poses a challenge in the clinician’s differential ***,the drug was important in treating gout;however,clinical studies are currently underway regarding the use of colchicine in patients with coronavirus disease 2019 as well as its use in coronary artery disease,making this drug more important in clinical *** SUMMARY A 61-year-old male with a history of gout and chronic colchicine intake was admitted to our Emergency Department due to numbness and weakness of the lower *** patient reported a history of colchicine intake for 23 *** thorough examination,he was diagnosed with colchicine poisoning,manifesting as neuromyopathy,multiple gastric ulcers and *** advised him to stop taking colchicine and drinking *** also provided a prescription of lansoprazole and mecobalamin,and then asked him to return to the clinic for *** patient was followed up for 3-mo during which time his gout symptoms were controlled to the point where he was *** Colchicine overdose can mimic the clinical manifestations of several *** easily pay attention to the disease while ignoring the cause of the ***,the patient’s medication history should never be ignored.
维普期刊数据库