Treatment for subtrochanteric fracture and subsequent nonunion in an adult patient with osteopetrosis:A case report and review of the literature
作者机构：Department of OrthopedicsThe Second Hospital of Jilin UniversityChangchun 130041Jilin ProvinceChina Departments of OrthopedicsThe Second Hospital of Jilin UniversityChangchun 130041Jilin ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2021年第9卷第35期
页 面：11007-11015页
核心收录：
学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题：Osteopetrosis Subtrochanteric fracture Nonunion Platelet-rich plasma Radial extracorporeal shock wave therapy Case report
摘 要：BACKGROUND As a congenital metabolic bone disease caused by defective osteoclastic resorption of immature bone,osteopetrosis is characterized by diffused sclerosis of bones,brittle bones,easy fracturing,narrow medullary canals,and a weak fracture healing *** present,clear standards and principles for the treatment of fractures in patients with osteopetrosis are ***-operative treatment can prevent fracture hematoma and preserve the blood supply to the bone fragments,while being associated with frequent failures and higher mortality ***,closed reduction and internal fixation with intramedullary nail(CRIF+IMN)approaches can also protect blood supply to the fracture ***,IMN cannot be used for the vast majority of patients with osteopetrosis due to the narrowing of medullary ***,open reduction and internal fixation with plate remains the most appropriate surgical method for treating fractures in patients with osteopetrosis,but this approach is complicated by the lack of intramedullary hematopoiesis in such *** healing primarily depends on the blood supply to the external *** reduction can also easily destroy the periosteum and cause delayed fracture healing or even nonunion;however,CRIF may be the most practical *** a result,it would be prudent to solve the difficulty of drilling during the operation and the problem of postoperative *** SUMMARY In 2018,we treated an adult patient with osteopetrosis presenting with a subtrochanteric *** fracture was fixed using a femoral locking compression *** of delayed consolidation,at 12 mo postoperatively the patient was further treated with platelet-rich plasma(PRP)combined with radial extracorporeal shock wave therapy(rESWT).Antero-posterior and lateral radiographs obtained at the latest follow-up(10 mo)showed that the callus had grown at the original fracture site,and the medial fracture line almost *** Ost
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