Solid extraintestinal malignancies in patients with inflammatory bowel disease

作     者：Anastasia Mala Kalliopi Foteinogiannopoulou Ioannis E Koutroubakis 

作者机构：University Hospital of HeraklionHeraklion 71110CreteGreece Department of GastroenterologyUniversity Hospital of HeraklionHeraklion 71110CreteGreece 

出 版 物：《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志（英文版）（电子版）)

年 卷 期：2021年第13卷第12期

页      面：1956-1980页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100214[医学-肿瘤学] 10[医学] 

主　　题：Extraintestinal malignancies Crohn’s disease Ulcerative colitis Thiopurines Anti-tumor necrosis factor 

摘      要：Malignancies constitute the second cause of death in patients with inflammatory bowel diseases(IBD),after cardiovascular *** it has been postulated that IBD patients are at greater risk of colorectal cancer compared to the general population,lately there has been evidence supporting that this risk is diminishing over time as a result of better surveillance,while the incidence of extraintestinal cancers(EICs)is *** could be attributed either to systemic inflammation caused by IBD or to long-lasting immunosuppression due to IBD *** seems that the overall risk of EICs is higher for Crohn’s disease patients and it is mainly driven by skin cancers,and liver-biliary cancers in patients with IBD and primary sclerosing *** aims of this review were first to evaluate the prevalence,characteristics,and risk factors of EICs in patients with IBD and second to raise awareness regarding a proper surveillance program resulting in early diagnosis,better prognosis and survival,especially in the era of new IBD treatments that are on the way.