Risk factors for post-endoscopic retrograde cholangiopancreatography(ERCP) abdominal pain in patients without post-ERCP pancreatitis

作     者：Meng-Jie Chen Ru-Hua Zheng Jun Cao Yu-Ling Yao Lei Wang Xiao-Ping Zou Meng-Jie Chen;Ru-Hua Zheng;Jun Cao;Yu-Ling Yao;Lei Wang;Xiao-Ping Zou

作者机构：Department of GastroenterologyNanjing Drum Tower Hospital Clinical College of Nanjing Medical UniversityNanjingChina Department of GastroenterologyAffiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjingChina 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2022年第21卷第3期

页      面：285-292页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by a grant from the National Natural Science Foundation of China(81871947) 

主　　题：Post-ERCP abdominal pain Cholangiopancreatography Endoscopic retrograde Pancreatitis Risk factor 

摘      要：Background:Abdominal pain is often observed after endoscopic retrograde cholangiopancreatography(ERCP).Few studies have focused on the risk factors of post-ERCP abdominal pain without post-ERCP pancreatitis(PEP).This study aimed to identify risk factors of post-ERCP abdominal pain without PEP and investigate characteristics of the abdominal pain in non-PEP ***:Data from patients who underwent ERCP from August 2019 to January 2020 were retrospectively *** of the abdominal pain after ERCP were recorded and compared between PEP and non-PEP *** analysis was conducted to identify risk factors of non-PEP abdominal ***:A total of 1295 ERCP procedures were investigated in this study,among which 100(7.72%)patients presented post-ERCP abdominal pain without PEP and 63(4.86%)patients with *** analysis found 9 risk factors of non-PEP abdominal pain:age≤65 years[odds ratio(OR):1.971],primary ERCP(OR:2.442),dilated extrahepatic bile duct(OR:1.803),no papilla opening(OR:2.095),pancreatic guidewire passages(OR:2.258),white blood cells(WBC)≤6.0×10^(9)/L(OR:1.689),platelet(PLT)≤250×10^(9)/L(OR:2.505),serumγ-glutamyl transferase(γ-GT)≤35 U/L(OR:2.190),and albumin≥40 g/L(OR:1.762).The PEP group had later pain onset,higher pain frequency and longer hospital stay than those of the non-PEP pain group(P0.05).Conclusions:This study indicated that age≤65 years,primary ERCP,dilated extrahepatic bile duct,no papilla opening,pancreatic guidewire passages,lower WBC,lower PLT,normalγ-GT and elevated albumin were independent risk factors for post-ERCP abdominal pain without *** pain occurred earlier in non-PEP patients than in PEP patients.