Performance of Cardiovascular Risk Equations versus Vascular Ultrasound in Systemic Lupus Erythematosus in a Black African Population

作     者：Sow Maïmouna Kane Baïdy Sy Diouf Marguerite Téning Aw Fatou Ndao Awa Cheikh Samba Abdourahmane Ndiaye Mouhamadou Bamba Ndongo Souhaibou Diao Maboury Pouye Abdoulaye Sow Maïmouna;Kane Baïdy Sy;Diouf Marguerite Téning;Aw Fatou;Ndao Awa Cheikh;Samba Abdourahmane;Ndiaye Mouhamadou Bamba;Ndongo Souhaibou;Diao Maboury;Pouye Abdoulaye

作者机构：Internal Medecine Department of Aristide Le Dantec Teaching Hospital of Dakar Senegal Cardiology Department of Aristide Le Dantec Teaching Hospital of Dakar Senegal Biochemial Department of Aristide Le Dantec Teaching Hospital of Dakar Senegal Internal Medecine Department of Dalal Jamm Hospital of Dakar Senegal 

出 版 物：《World Journal of Cardiovascular Diseases》 (心血管病（英文）)

年 卷 期：2021年第11卷第11期

页      面：523-532页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Cardiovascular Risk Equations Carotid Ultrasound Systemic Lupus Erythematosus 

摘      要：Introduction: Cardiovascular risk is increased in systemic lupus erythematosus. Cardiovascular events are the first cause of death in lupus after five years duration. Prevention of cardiovascular events needs a good evaluation of the risk. In this work, we tried to evaluate the performance of conventional and adjusted forms of cardiovascular risk equations to predict high risk in lupus patients, in comparison with carotid ultrasound. Method: We realized a cross-sectional study during the period from 24 August 2017 to 22 November 2018. Consenting patient meeting the 1997 American college of Rheumatology criteria of systemic lupus erythematosus were recruited. The clinical characteristics and the treatment data were informed. Traditional cardiovascular risk factors were also investigated, and the assessment of cardiovascular risk was performed by Framingham and SCORE equations and their modified forms (multiplication by a factor of 1.5). Carotid ultrasound was used to detect atherosclerosis by measuring intima media thickness and searching for carotid plaques. In last, we compared cardiovascular risk levels by equations to results of carotid ultrasound. Statistical analysis and data collection were performed using SPSS 23.0 software. Results: Forty-nine patients with a sex ratio of 0.13 and a mean age of 33.5 (±11.3) years were enrolled. More than half of patients had dyslipidemia. More than 80% of the population were at lo