Extracranial multiorgan metastasis from primary glioblastoma: A case report
作者机构：Department of NeurosurgeryThe Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Sichuan Clinical Research Center for NeurosurgerySouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Academician(Expert)Workstation of Sichuan ProvinceSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of PathologyThe Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2021年第9卷第33期
页 面：10300-10307页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by Medical Research Fund for Young Scholars of the Sichuan Medical Association,No.Q16076 Natural Science Foundation of Southwest Medical University,No.2016XNYD217 and Science and Technology Projects of Sichuan Province,No.2018JY0403
主 题：Glioblastoma Extracranial metastasis Multiple organ metastasis Primary glioblastoma Case report
摘 要：BACKGROUND Glioblastoma has a high degree of malignancy and poor *** is common to have in situ recurrence and intracranial metastasis,while extracranial metastasis is rare,and extracranial multiorgan metastasis is extremely *** report a case of glioblastoma with extracranial multiorgan metastasis,which will strengthen clinicians’attention to the extracranial metastasis of glioblastoma and its *** SUMMARY A male patient visited our hospital for treatment of dizziness and *** resonance imaging of the brain revealed a space-occupying lesion in the right temporoparietal occipital *** computed tomography and abdominal ultrasound were normal,and no space-occupying lesions were observed in other organs of the *** patient underwent surgery and diagnosed with *** concurrent radiotherapy and chemotherapy were *** the follow-up,the tumor was found to have metastasized to the scalp and neck,and a second tumor resection was *** follow-up revealed extracranial metastases to multiple extracranial organs including skull,scalp,ribs,spine,liver and *** family members refused further treatment,and requested only symptomatic treatment such as pain relief,and the patient died of systemic multiple organ *** time from diagnosis to death was 13 mo and from extracranial metastasis to death was 6 *** Glioblastoma extracranial metastasis is extremely rare,clinicians should always pay attention to its *** mechanism of glioblastoma extracranial metastasis is still unclear,and genetic and molecular studies are required.
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