Retina cell atlases of multiple species and an online platform for retina cell-type markers
Retina cell atlases of multiple species and an online platform for retina cell-type markers作者机构:College of Life SciencesUniversity of Chinese Academy of SciencesBeijing 100049China BGI-ShenzhenShenzhenGuangdong 518083China Department of Computer ScienceCity University of Hong KongHong Kong 999077China Tsinghua-Berkeley Shenzhen Institute(TBSI)Tsinghua UniversityShenzhenGuangdong 518055China Department of PhysiologySchool of Basic Medical SciencesBinzhou Medical UniversityYantaiShandong 264003China Fujian Key Laboratory of Developmental and Neural BiologyCollege of Life SciencesFujian Normal UniversityFuzhouFujian 350117China Cuiying Biomedical Research CenterLanzhou University Second HospitalLanzhouGansu 730010China Institute of PediatricsDepartment of Pediatric SurgeryShenzhen Children's HospitalShenzhenGuangdong 51803&China Department of PediatricsThe Affiliated Hospital of Guangdong Medical UniversityZhanjiangGuangdong 524001China
出 版 物:《Journal of Genetics and Genomics》 (遗传学报(英文版))
年 卷 期:2022年第49卷第3期
页 面:262-265页
核心收录:
学科分类:0710[理学-生物学] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 090102[农学-作物遗传育种]
基 金:supported by China National Gene Bank (CNGB) financially supported by funding from the National Natural Science Foundation of China (31670742) the Guangdong Natural Science Foundation (2021A1515011109)
摘 要:The retina is a complex visual tissue that perceives light signals because of an exquisite orchestration of high cellular complexity(Fig. 1A). It is of great significance to explore the transcriptome diversity of each cell type for comprehensive understanding(Voigt et al.,2020b). Unlike conventional sequencing methods, single-cell RNAsequencing(scRNA-seq) and single-nucleus RNA-sequencing(snRNA-seq) accurately profile transcriptomic characterization of individual whole cells and nuclei, respectively.