Systematic review of novel ablative methods in locally advanced pancreatic cancer
Systematic review of novel ablative methods in locally advanced pancreatic cancer作者机构：Institute for Liver and Digestive Health University College London Royal Free Campus London NW3 2PF United Kingdom HPB and Liver Transplant Unit Royal Free Hospital London NW3 2QG United Kingdom
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2014年第20卷第9期
页 面：2267-2278页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by National Institutes of Health Grant PO1CA84203 The work was undertaken at UCLH/UCL,which receives a proportion of funding from the Department of Health’s National Institute for Health Research Biomedical Research Centres fundingscheme A CRUK research bursary to Keane MG
主 题：Pancreatic cancer Radiofrequency ablation Photodynamic therapy Cryoablation Microwave ablation High frequency focused ultrasound Irreversible electroporation
摘 要：Unresectable locally advanced pancreatic cancer with or without metastatic disease is associated with a very poor *** standard therapy is limited to chemotherapy or *** regimens have been shown to have a substantial survival advantage and novel treatment strategies are urgently *** and laser based ablative techniques are widely used in many solid organ *** studies in the pancreas were associated with significant morbidity and mortality,which limited widespread *** to the various applications,in particular combining the techniques with high quality imaging such as computed tomography and intraoperative or endoscopic ultrasound has enabled real time treatment monitoring and significant improvements in *** conducted a systematic review of the litera-ture up to October *** studies suggest that ablative therapies may confer an additional survival benefit over best supportive care but randomised studies are required to validate these findings.
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