Numerical simulation of effect of convection-diffusion on oxygen transport in microcirculation

作     者：N.ZHAO K.IRAMINA 

作者机构：Graduate School of Systems Life Sciences Kyushu University Department of Informatics Graduate School of Information Science and Electrical Engineering Kyushu University 

出 版 物：《Applied Mathematics and Mechanics(English Edition)》 (应用数学和力学（英文版）)

年 卷 期：2015年第36卷第2期

页      面：179-200页

核心收录：

学科分类：07[理学] 0805[工学-材料科学与工程（可授工学、理学学位）] 070102[理学-计算数学] 0802[工学-机械工程] 0701[理学-数学] 0801[工学-力学（可授工学、理学学位）] 

主　　题：porous medium microcirculation oxygen transport convection-diffusion solid deformation fluid seepage 

摘      要：The entire process of oxygen transport in microcirculation by developing a3 D porous media model is calculated numerically with coupled solid deformation-fluid seepage-convection and diffusion. The principal novelty of the model is that it takes into account volumetric deformation of both capillary and tissues resulting from capillary fluctuation. How solid deformation, fluid seepage, and convection-diffusion combine to affect oxygen transport is examined quantitatively：（1） Solid deformation is more significant in the middle of capillary, where the maximum value of volumetric deformation reaches about 0.5%.（2） Solid deformation has positive influence on the tissue fluid so that it flows more uniformly and causes oxygen to be transported more uniformly, and eventually impacts oxygen concentration by 0.1%–0.5%.（3） Convection-diffusion coupled deformation and seepage has a maximum（16%） and average（3%） increase in oxygen concentration,compared with pure molecular diffusion. Its more significant role is to allow oxygen to be transported more evenly.