Cancer immunology and immunotherapy

作     者：Xiubao Ren Xiubao Ren

作者机构：Department of ImmunologyTianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China Department of BiotherapyTianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerTianjin 300060China Key Laboratory of Cancer Prevention and TherapyTianjin’s Clinical Research Center for CancerKey Laboratory of Cancer Immunology and BiotherapyTianjin 300060China 

出 版 物：《Cancer Biology & Medicine》 (癌症生物学与医学（英文版）)

年 卷 期：2021年第18卷第4期

页      面：931-933页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：immunotherapy sarcoma cancer 

摘      要：At the beginning of the last century,*** Coley introduced“Coley’s toxinto the scientific community after observing that a small number of patients with sarcoma with infections developed spontaneous tumor regression.“Coley’s toxinconsisted of bacteria or bacterial products and achieved a durable response in a small group of patients with cancer,most of whom had inoperable ***,this response was usually unpredictable because of the lack of understanding of the immune response at that *** then,researchers have continued to study the relationship between cancer and the host immune system,and the discovery of“Coley’s toxinmarked the beginning of cancer immunotherapy^(1).