Impact of COVID-19 pandemic on the neuropsychiatric status of Wilson’s disease

作     者：Giuseppe Lanza Massimiliano Godani Raffaele Ferri Alberto Raggi 

作者机构：Department of Surgery and Medical-Surgical SpecialtiesUniversity of CataniaCatania 95123Italy Clinical Neurophysiology Research UnitOasi Research Institute-IRCCSTroina 94018Italy Neurology UnitSant’Andrea Civic HospitalLa Spezia 19121Italy Department of Neurology ICSleep Research CenterOasi Research Institute-IRCCSTroina 94018Italy Unit of NeurologyG.B.Morgagni-L.Pierantoni HospitalForlì47121Italy 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2021年第27卷第39期

页      面：6733-6736页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：Wilson’s disease Extra-hepatic manifestations Neuropsychiatric symptoms COVID-19 Therapy Resilience 

摘      要：We have read with interest the Letter to the Editor by *** and Zhong,who presented the clinical data of 68 patients with Wilson’s disease(WD)who were admitted to the hospital before and during the coronavirus disease 2019(COVID-19)pandemic,and appreciated their findings on hepatic and some extrahepatic ***,given the strong impact of the pandemic on patients with neurological and psychiatric disorders,we would have expected a worsening of the psychiatric and/or neurological impairments in these *** contrast,according to the authors,these manifestations remained,somewhat unexpectedly,*** finding is in contrast with most of the current literature that highlights not only an increased incidence of mental health disorders in the general population but also an exacerbation of neurological and psychiatric symptoms in patients with chronic diseases,especially in those with pre-existing neuropsychiatric disorders,such as *** the study was mainly focused on the hepatic features of WD patients taking anti-copper treatment,a generic and cumulative definition of neurological and psychiatric manifestations,as in this study,does not allow for further *** studies during and after the pandemic are necessary to clarify the real impact,either direct or indirect,of the COVID-19 pandemic on the neurological and psychiatric symptoms of WD patients.