Adaptive alterations of elastic fibers in the bilaminar zone of rabbit temporomandibular joint following disc displacement

作     者：谷志远 吴慧玲 冯剑颖 柴田考典 胡济安 张银凯 谢志坚 GU Zhiyuan;Wu Huiling;FENG Jianying;SHIBATA Takanori;HU Ji'an;ZHANG Yinkai;Xie Zhijian

作者机构：浙江大学医学院附属口腔医院口腔颌面外科杭州310006 浙江大学医学院附属第一医院外科杭州310006 日本山形大学医学部口腔颌面外科 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2002年第115卷第12期

页      面：1772-1776,144页

核心收录：

学科分类：1003[医学-口腔医学] 100302[医学-口腔临床医学] 10[医学] 

主　　题：Adaptation, Physiological Animals Behavior, Animal Dislocations Elastic Tissue Extracellular Matrix Rabbits Temporomandibular Joint Disk Temporomandibular Joint Disorders 

摘      要：OBJECTIVE: To study the adaptive alterations of elastic fibers in the bilaminar zone (BZ) of rabbit temporomandibular joint (TMJ) following disc displacement. METHODS: Twenty-eight Japanese white rabbits were used in this study. The right temporomandibular joints of 20 of 28 rabbits were subjected to the surgical procedure of anterior disc displacement (ADD). Four rabbits in the surgical group were sacrificed at 2, 4, 6, 8 and 12 weeks after operation. Their temporomandibular joints were studied histochemically. RESULTS: Elastic fibers were reduced in number and ran irregularly in the superior lamina of BZ from ADD rabbits. The jungly elastic fibers (EFs) could still be seen at 2 weeks after operation. At 4 weeks, the number of EFs decreased significantly; EFs lost their jungly arrangement and were shaped like rough dots, of which the arrangement and the lengths were different. Six weeks after operation, many EFs were replaced by distorted, uneven, non-oriented fine EFs, distributed unevenly and some thick or fine EFs that ran irregularly. The number of EFs decreased further and their arrangement was more deranged at 8 weeks. At 10 and 12 weeks, EFs in the superior lamina of BZ were similar to those at 8 weeks. CONCLUSION: Our results show that EFs lost their function as well as their distribution and arrangement after disc displacement.