Fatigue behavior of cortical bone:a review

作     者：Jingwen Li He Gong Jingwen Li;He Gong

作者机构：Key Laboratory for Biomechanics and Mechanobiology of Ministry of EducationBeijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijing 100191China 

出 版 物：《Acta Mechanica Sinica》 (力学学报（英文版）)

年 卷 期：2021年第37卷第3期

页      面：516-526,I0004页

核心收录：

学科分类：08[工学] 0802[工学-机械工程] 0701[理学-数学] 0801[工学-力学（可授工学、理学学位）] 080102[工学-固体力学] 0702[理学-物理学] 

基　　金：This study was supported by the National Natural Science Foundation of China(Grant 11872095) the Natural Science Foundation of Jilin Province(Grant 20200201260JC). 

主　　题：Cortical bone Fatigue Microdamage Influential factor 

摘      要：Fatigue is a common cause of bone failure.As the main load-bearing tissue,cortical bone carries a considerable share of load in the whole bone.Under cyclic loading condition,microdamage may generates and accumulates in cortical bone,which further triggers the fracture of bone.It is crucial to explore the fatigue properties of cortical bone and the influential factors for both clinical diagnosis and establishment of models that can predict fatigue failure of human cortical bone.In this review,the fatigue behavior of cortical bone was investigated.Through the complex hierarchical structure and self-repairing process,the risk of catastrophic fracture is reduced.Based on these understandings,the multiple influential factors of cortical bone fatigue properties were analyzed,which were considered to be a combination of internal and external factors.The internal factors include material properties of bone composition(i.e.,mineral,organic material,and water)and bone structure.External factors refer to loading condition such as frequency,amplitude and direction of load.Besides,age,disease,radiation exposure and other factors affect the fatigue behavior of bone by altering one or more factors mentioned above.