Acute respiratory distress syndrome:focusing on secondary injury

作     者：Pan Pan Long-Xiang Su Da-Wei Liu Xiao-Ting Wang on behalf of the Chinese Critical Ultrasound Study Group(CCUSG) Pan Pan;Su Long-Xiang;Liu Da-Wei;Wang Xiao-Ting;on behalf of the Chinese Critical Ultrasound Study Group (CCUSG)

作者机构：College of Pulmonary and Critical Care MedicineThe General Hospital of the People’s Liberation ArmyBeijing 100091China Department of Critical Care MedicinePeking Union Medical College and Chinese Academy of Medical SciencesBeijing 100730China 不详 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2021年第134卷第17期

页      面：2017-2024页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：This study was supported by grants from the China Postdoctoral Science Foundation(No.2021T140794). 

主　　题：Acute respiratory distress syndrome Secondary lung injury Spontaneous breathing Pulmonary circulation Sedation 

摘      要：Acute respiratory distress syndrome(ARDS)is one of the most common severe diseases seen in the clinical setting.With the continuous exploration of ARDS in recent decades,the understanding of ARDS has improved.ARDS is not a simple lung disease but a clinical syndrome with various etiologies and pathophysiological changes.However,in the intensive care unit,ARDS often occurs a few days after primary lung injury or after a few days of treatment for other severe extrapulmonary diseases.Under such conditions,ARDS often progresses rapidly to severe ARDS and is difficult to treat.The occurrence and development of ARDS in these circumstances are thus not related to primary lung injury;the real cause of ARDS may be the“second hitcaused by inappropriate treatment.In view of the limited effective treatments for ARDS,the strategic focus has shifted to identifying potential or high-risk ARDS patients during the early stages of the disease and implementing treatment strategies aimed at reducing ARDS and related organ failure.Future research should focus on the prevention of ARDS.