Seroprevalence of anti-HBs antibodies and the need for booster vaccination in children under 5 years of age born to HBsAg-negative mothers
作者机构：Medical SchoolFaculty of MedicineUniversitas AirlanggaIndonesia Department of Internal MedicineDr.Soetomo General Hospital/Faculty of MedicineUniversitas AirlanggaIndonesia Department of PediatricsDr.Soetomo General Hospital/Faculty of MedicineUniversitas AirlanggaIndonesia Department of Medical MicrobiologyFaculty of MedicineUniversitas AirlanggaIndonesia
出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)
年 卷 期：2021年第14卷第9期
页 面：410-416页
核心收录：
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
主 题：Hepatitis B vaccination Booster vaccine Children under five years
摘 要：Objective:To determine the proportion of HBV surface antigen(anti-HBs)antibody positive children under five years of age born to HBs Ag-negative mothers and to analyze the possible related factors following implementation of a hepatitis B vaccination program for infants in Indonesia 22 years ***:Blood samples were taken from children under five years of age born to HBsAg-negative mothers who have completed primary vaccination ***-HBs antibodies were determined by using rapid *** of age,gender,nutritional status,vaccination timing or vaccination compliance,and booster vaccination were collected from vaccination ***:Ninety children were enrolled,consisting of 47 females and 43 males with a mean age of 2.3 *** two(24.4%)children received booster vaccine between 18 and 24 months and 55(61.1%)were anti-HBs *** factors of age,gender,nutritional status,compliance to vaccination and booster vaccine,only administration of booster vaccine was significantly associated with anti-HBs status(OR 5.45,95%CI 1.45,20.52).Children who received booster vaccine at age of 18-24 months were 5.45 times more likely to be anti-HBs positive than that of children who did not receive booster ***:Booster vaccine rate is low among children under 5 years of age but is associated with anti-HBs *** vaccination may be required to improve anti-HBs seropositivity.
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