K_(2)S_(2)O_(8)-mediated acylarylation of unactivated alkenes via acyl radical addition/C–H annulation cascade of N-allyl-indoles with silver cocatalysis
作者机构：Key Laboratory of Functional Molecular Solids(Ministry of Education)Anhui Key Laboratory of Molecular Based MaterialsCollege of Chemistry and Materials ScienceAnhui Normal UniversityWuhu 241002China.
出 版 物：《Organic Chemistry Frontiers》 (有机化学前沿（英文）)
年 卷 期：2022年第9卷第1期
页 面：32-38页
核心收录：
学科分类：081704[工学-应用化学] 07[理学] 0806[工学-冶金工程] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金：the National Natural Science Foundation of China(21702237,21272004) the Natural Science Research Project for Anhui Universities,the Start-up Research Fund of Anhui Normal University and the Project for Students’Innovative Experiment of Anhui Normal University for their financial support
摘 要：A silver-catalyzed,K_(2)S_(2)O_(8)-mediated protocol to access regioselective acylarylation of unactivated alkenes was *** reaction between N-allyl-indoles andα-oxocarboxylic acids proceeded smoothly and involved an acyl radical addition/C–H cyclization *** protocol showed a broad substrate scope and good tolerance of functional *** reaction proceeded with both internal and terminal alkenes to furnish many functional pyrrolo[1,2-a]indoles bearing the ketone carbonyl group,and this feature also provides the potential to construct structurally complex N-containing heterocycles.
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