Exclusive Hormonal Therapy in Breast Cancer in Elderly Women:Clinical Response and Survival over 10 Years
作者机构：Unitéde gynécologie et Obstétrique/FSS-universitéd’Abomey CalaviCotonouBP 188Bénin Facultédes sciences médicales et paramédicales-Aix-Marseille université13284 Marseille Cedex 07France Centre hospitalier Intercommunal Aix-Pertuis13616 Aix en Provence Cedex 01France Département de santépublique/FSS-universitéd’Abomey CalaviCotonouBP 188Bénin
出 版 物：《Journal of Pharmacy and Pharmacology》 (药剂与药理学（英文版）)
年 卷 期：2021年第9卷第9期
页 面：296-302页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Exclusive hormonal therapy neoadjuvant hormonal therapy elderly women breast cancer clinical response cancer survival cancer mortality cancer France
摘 要：Breast cancer is the first cancer of women in the world and in *** very elderly patients,the treatment options are often very *** hormone therapy has shown similar or even better results than *** is why we decided to evaluate the clinical response following exclusive hormonal therapy and the 5,then 10 years survival in these very elderly *** was a retrospective,longitudinal cohort-type study with descriptive and analytical *** study population consisted of 59 patients,with an average age of 85 ***(15,25%)of our patients had a complete clinical response after two years of treatment,16(27%)a partial clinical response,23(39%)lesion stabilization and 5(9%)cancer *** presence of metastasis at diagnosis increased the risk of cancer progression by *** 5-year survival was 72.5%,and breast cancer mortality 5.88%.The 10-year survival was 27.5%and breast cancer mortality 15%.In the age group 85 and over increased the risk of death by 3.25 in the first 10 years of *** clinical response after 2 years was marked by a low rate of cancer *** over 5 and 10 years was mostly related to patient comorbidities.
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