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Prevalence of Bacteremia among the HIV and Non HIV Infected Patients Visiting Alupe Sub Hospital, Alupe Division of Teso South Sub-County, Busia County, Kenya between 2017 and 2019

Prevalence of Bacteremia among the HIV and Non HIV Infected Patients Visiting Alupe Sub Hospital, Alupe Division of Teso South Sub-County, Busia County, Kenya between 2017 and 2019

作     者:Anne N. Mutsami Caroline Ngugi John Kiiru Anne N. Mutsami;Caroline Ngugi;John Kiiru

作者机构:Department of Medical Microbiology School of Biomedical Sciences Jomo Kenyatta University of Agriculture and Technology Juja Kenya Department of Microbiology Kenya Medical Research Institute Nairobi Kenya 

出 版 物:《Open Journal of Medical Microbiology》 (医学微生物学(英文))

年 卷 期:2021年第11卷第3期

页      面:249-266页

学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主  题:Prevalence Salmonella ssp Klebsiella ssp Escherichia coli Isolates 

摘      要:Background: Bacteremia is the presence of viable bacteria in circulating blood. This is common in HIV patients, leading to a significant publichealth problem worldwide. It is concomitant with upraising cases of antibiotic resistance that results in high morbidity rates leading to increased hospital visits and high mortality rates. Gram-negative bacteria which produce extended-spectrum β-lactamase (ESBL) are becoming more common and pathogenic in this group of people. Genes responsible for resistance are well-known to spread among various microorganisms. By employing a case-control study design, this study determined prevalence of bacteremia in Salmonella ssp, Klebsiella ssp, and Escherichia coli in HIV positive and HIV negative patients attending Alupe subcounty hospital. Methods: A total of 113 HIV positive and 133 HIV negative patients were sampled purposively grounded on Lameshow sample size determination formula. Consent was sought from the study participants followed by questionnaire administration. Blood (10ml) was collected from each enrolled patient and later subjected tofull haemogram (1ml), Salmonella Antigen test (1ml) and general bacterial isolation (8ml). Results: HIV positive pati

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