Laparoscopic myomectomy versus open myomectomy in uterine fibroid treatment: A meta-analysis

作     者：Probo Yudha Pratama Putra Arlinda Silva Prameswari Mochammad Ma'roef Aida Musyarrofah Halida Nelasari Probo Yudha Pratama Putra;Arlinda Silva Prameswari;Mochammad Ma'roef;Aida Musyarrofah;Halida Nelasari

作者机构：Medical FacultyUniversity of Muhammadiyah MalangMalangIndonesia Department Obstetric and GynecologyMedical FacultyUniversity of Muhammadiyah MalangMalangIndonesia Department Obstetric and GynecologyGeneral Hospital of University Muhammadiyah MalangMalangIndonesia 

出 版 物：《Laparoscopic, Endoscopic and Robotic Surgery》 (腔镜、内镜与机器人外科（英文）)

年 卷 期：2021年第4卷第3期

页      面：66-71页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Uterine fibroid Laparoscopic myomectomy Open myomectomy 

摘      要：Objective:Uterine fibroids are the most commonly occurring benign solid tumors in women,and laparoscopic or open myomectomy constitutes the primary option for ***,both methods are under debate currently in terms of efficacy and *** this meta-analysis we assessed the efficacy and safety of the two ***:We conducted a comprehensive literature search of PubMed,ScienceDirect,and the Cochrane Library in December *** search terms included“open myomectomy,“myomectomies,“laparoscopic,and“uterine fibroids.We then selected the randomized control trials published from 1996 to 2019 and compared laparoscopic and open ***:We included 10 studies of 449 patients who underwent laparoscopic myomectomy and 449 patients who underwent open *** data revealed that laparoscopic myomectomy was associated with reduced blood loss(MD=-34.43;95%CI,-34.92 to-33.94;p0.001),an attenuated decline in hemoglobin(MD=-1.04;95%CI,-1.14 to -0.93;p0.001),less post-operative pain at 24 h(MD=-0.51;95%CI,-0.83 to -0.19;p=0.002),and fewer overall complications(OR=0.42;95%CI,0.24 to 0.71;p=0.001)relative to open myomectomy;but the former possessed a longer operative time(MD=12.96;95%CI,9.94 to 15.97;p0.001).There were no significant differences in pregnancy rate(OR=1.39;95%CI,0.72 to 2.68;p=0.33)or recurrence rate of postoperative uterine fibroids(OR=1.15;95%CI,0.60 to 2.18;p=0.67)between the two ***:Laparoscopic myomectomy displayed superior results compared to open myomectomy,although the former involved a longer operating time.