Outcomes of inpatient cholecystectomy among adults with cystic fibrosis in the United States

作     者：Mitchell L Ramsey Lindsay A Sobotka Somashekar G Krishna Alice Hinton Stephen E Kirkby Susan S Li Michael P Meara Darwin L Conwell Peter P Stanich 

作者机构：Division of GastroenterologyHepatology and NutritionThe Ohio State University Wexner Medical CenterColumbusOH 43210United States Division of BiostatisticsThe Ohio State University College of Public HealthColumbusOH 43210United States Division of Pulmonary and Critical Care MedicineThe Ohio State University Wexner Medical CenterColumbusOH 43210United States Division of General Internal MedicineThe Ohio State University Wexner Medical CenterColumbusOH 43210United States Division of General and Gastrointestinal SurgeryThe Ohio State University Wexner Medical CenterColumbusOH 43210United States 

出 版 物：《World Journal of Gastrointestinal Endoscopy》 (世界胃肠内镜杂志（英文版）（电子版）)

年 卷 期：2021年第13卷第9期

页      面：371-381页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Laparoscopic cholecystectomy Nationwide Inpatient Sample Cystic fibrosis Mortality Length of stay Symptomatic biliary disorders 

摘      要：BACKGROUND Symptomatic biliary and gallbladder disorders are common in adults with cystic fibrosis(CF)and the prevalence may rise with increasing CF transmembrane conductance regulator modulator *** may be considered,but the outcomes of cholecystectomy are not well described among modern patients with *** To determine the risk profile of inpatient cholecystectomy in patients with *** The Nationwide Inpatient Sample was queried from 2002 until 2014 to investigate outcomes of cholecystectomy among hospitalized adults with CF compared to controls without CF.A propensity weighted sample was selected that closely matched patient demographics,patient’s individual comorbidities,and hospital *** propensity weighted sample was used to compare outcomes among patients who underwent laparoscopic *** outcomes of open and laparoscopic cholecystectomy were compared among adults with *** A total of 1239 inpatient cholecystectomies were performed in patients with CF,of which 78.6%were performed *** was0.81%,similar to those without CF(P=0.719).In the propensity weighted analysis of laparoscopic cholecystectomy,there was no difference in mortality,or pulmonary or surgical complications between patients with CF and *** adjusting for significant covariates among patients with CF,open cholecystectomy was independently associated with a 4.8 d longer length of stay(P=0.018)and an$18449 increase in hospital costs(P=0.005)compared to laparoscopic *** Patients with CF have a very low mortality after cholecystectomy that is similar to the general *** patients with CF,laparoscopic approach reduces resource utilization and minimizes post-operative complications.