Gastric neuroendocrine neoplasms: A review
作者机构：Department of GastroenterologyHitit UniversityFaculty of MedicineCorum 19200Turkey Department of GastroenterologyHitit University Erol Olcok Education and Research HospitalCorum 19200Turkey
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2021年第9卷第27期
页 面：7973-7985页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Gastric neuroendocrine tumors Gastric neuroendocrine neoplasm Gastric neuroendocrine carcinoma Hypergastrinemia Carcinoid Somatostatin receptor imaging
摘 要：Gastric neuroendocrine neoplasms(g-NENs)or neuroendocrine tumors are generally slow-growing tumors with increasing *** arise from enterochromaffin like cells and are divided into four types according to clinical characteristic *** 1 and 2 are gastrin dependent,whereas type 3 and 4 are *** reason for hypergastrinemia is atrophic gastritis in type 1,and gastrin releasing tumor(gastrinoma)in type 2 *** diagnosis of g-NENs needs histopathological investigation taken by upper gastrointestinal endoscopy.g-NENs are positively stained with chomogranin A and *** is made with mitotic index and ki-67 proliferation index on histopathological *** is crucial to discriminate between types of g-NENs,because the management,treatment and prognosis differ significantly between *** options for g-NENs include endoscopic resection,surgical resection with or without antrectomy,medical treatment with somatostatin analogues,netazepide or chemotherapy ***-up without excision is another option in appropriate *** prognosis of type 1 and 2 g-NENs are good,whereas the prognosis of type 3 and 4 g-NENs are close to the prognosis of gastric adenocancer.
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