Comparison of pathological findings between patients with relapsed and non-relapsed immunoglobin G4-related disease

作     者：Hui Lu Shan Wang Mu Wang Xiaowei Liu Linyi Peng Jiaxin Zhou Jieqiong Li Zheng Liu Xuan Luo Yu Peng Yunyun Fei Yan Zhao Xiaofeng Zeng Ruie Feng Wen Zhang Hui Lu;Shan Wang;Mu Wang;Xiaowei Liu;Linyi Peng;Jiaxin Zhou;Jieqiong Li;Zheng Liu;Xuan Luo;Yu Peng;Yunyun Fei;Yan Zhao;Xiaofeng Zeng;Ruie Feng;Wen Zhang

作者机构：Department of RheumatologyPeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeNational Clinical Research Center for Dermatologic and Immunologic DiseasesState Key Laboratory of Complex Severe and Rare DiseasesBeijing 100730China Department of PathologyPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of StomatologyPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of OphthalmologyPeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2022年第135卷第4期

页      面：465-467页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：This work was supported by grants from the National Natural Science Foundation of China(Nos.81771757,81771780,82071839) the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences(No.NWB20203346) Capital’s Funds for Health Improvement and Research(No.2020-2-4017) Beijing Municipal Science and Technology Commission(No.Z201100005520023) 

主　　题：IgG4 relapse involvement 

摘      要：Immunoglobin(Ig)G4-related disease(IgG4-RD)is an immune-mediated fibroinflammatory condition characterized by elevated serum IgG4 levels and multi-organ *** characteristic histological findings of IgG4-RD are dense lymphoplasmacytic infiltration,fibrosis,and massive IgG4 positive plasma cells infiltrating the affected tissues.[1]Previous studies have demonstrated various relapse predictors corresponding to demographic,clinical characteristics,laboratory test results,and treatment ***,no study has revealed the risk factors of flares in *** study aimed to ascertain whether the pathological characteristics are related to therapeutic outcomes.