Textbook Outcome as a measure of surgical quality assessment and prognosis in gastric neuroendocrine carcinoma:A large multicenter sample analysis

作     者：Qiyue Chen Zhongliang Ning Zhiyu Liu Yanbing Zhou Qingliang He Yantao Tian Hankun Hao Wei Lin Lixin Jiang Gang Zhao Ping Li Chaohui Zheng Changming Huang on behalf of the Study Group for Gastric Neuroendocrine Tumors Qiyue Chen;Zhongliang Ning;Zhiyu Liu;Yanbing Zhou;Qingliang He;Yantao Tian;Hankun Hao;Wei Lin;Lixin Jiang;Gang Zhao;Ping Li;Chaohui Zheng;Changming Huang;on behalf of the Study Group for Gastric Neuroendocrine Tumors

作者机构：Department of Gastric SurgeryFujian Medical University Union HospitalFuzhou 350001China Department of General SurgeryFujian Medical University Union HospitalFuzhou 350001China Key Laboratory of Ministry of Education of Gastrointestinal CancerFujian Medical UniversityFuzhou 350004China Fujian Key Laboratory of Tumor MicrobiologyFujian Medical UniversityFuzhou 350004China Department of Gastrointestinal SurgeryWest District of the First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China Department of Gastrointestinal SurgeryAffiliated Hospital of Qingdao UniversityQingdao 266000China Department of Gastrointestinal Surgerythe First Affiliated Hospital of Fujian Medical UniversityFuzhou 350005China Department of Pancreatic and Gastric SurgeryNational Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of General SurgeryHuashan HospitalFudan UniversityShanghai 200040China Department of Gastrointestinal Surgery and Gastrointestinal Surgery Research Institutethe Affiliated Hospital of Putian UniversityPutian 351106China Department of Gastrointestinal SurgeryYantai Yuhuangding HospitalYantai 264099China Department of Gastrointestinal SurgeryRenji HospitalShanghai Jiaotong UniversityShanghai 200127China 不详 

出 版 物：《Chinese Journal of Cancer Research》 (中国癌症研究（英文版）)

年 卷 期：2021年第33卷第4期

页      面：433-446页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by scientific and technological innovation joint capital projects of Fujian province(No.2018Y9041) National Natural Science Foundation of China(No.82002462) China Scholarship Council(No.201908350095) Provincial Natural Science Foundation Project(No.2020J011001) Fujian Medical University Outstanding Young Cultivation Project(No.2020PYY002) 

主　　题：Textbook Outcome gastric neuroendocrine carcinoma surgical quality prognosis risk factor 

摘      要：Objective:Quality assurance is crucial for oncological surgical treatment *** rare diseases,singlequality indicators are not *** aim to develop a comprehensive and reproducible measurement,called theTextbook Outcome(TO),to assess the quality of surgical treatment and prognosis of gastric neuroendocrine carcinoma(G-NEC)***:Data from patients with primary diagnosed G-NEC included in 24 high-volume Chinese hospitals from October 2005 to September 2018 were *** included receiving a curative resection,≥15 lymph nodes examined,no severe postoperative complications,hospital stay≤21 d,and no hospital readmission≤30 d after *** variation in TO was analyzed using a case mix-adjusted funnel *** factors of survival and risk factors for non-Textbook Outcome(non-TO)were analyzed using Cox and logistic models,***:TO was achieved in 56.6%of 860 G-NEC *** patients had better overall survival(OS),disease-free survival(DFS),and recurrence-free survival(RFS)than non-TO patients(P200 mL blood loss were independent risk factors for non-TO patients(P0.05).Conclusions:TO is strongly associated with multicenter surgical quality and prognosis for G-NEC *** predicting non-TO are identified,which may help guide strategies to optimize G-NEC outcomes.