Polysaccharides from the Green Alga Ulva lactuca Improve Antioxidant Balance and Bone Mineral Density in Diabetic Rats

作     者：Sahla Belhadj Manel Gargouri Giulia Guerriero Olfa Hentati Sahla Belhadj;Manel Gargouri;Giulia Guerriero;Olfa Hentati

作者机构：UFR SciencesUniversity of BourgogneBoulevard Gabriel21000DijonFrance Laboratoire Génie de l'Environnement et Ecotechnologie(GEET-LR16ES19Ecole Nationale d'Ingénieurs de Sfax(ENIS)Universitéde SfaxRoute de SoukraSfaxTunisie Institute of TechnologyUniversity of BrestBrestFrance Department of BiologyUniversity of Naples FedericoⅡComplesso Universitario di Monte S.AngeloNaplesItaly Interdepartmental Research Center for EnvironmentUniversity of Naples FedericoⅡNaplesItaly Institut Supérieur de Biotechnologie de SfaxUniversitéde SfaxRoute de SoukraSfaxTunisie 

出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)

年 卷 期：2021年第34卷第8期

页      面：637-640页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：the Tunisian Ministry of Higher Education Scientific Research and Information and Communication Tech nologies 

主　　题：Antioxidant peroxidation elevated 

摘      要：Diabetes mellitus(DM),the 10th leading cause of death worldwide,is a major and growing public health problem estimated to affect more than 578 million people in 2030 and 700 million people in 2045[1].In diabetic animals,protein glycation and glucose autoxidation generate free radicals,which cause lipid ***,reactive oxygen species(ROS)can quickly accumulate,decrease antioxidant activity,and cause deterioration of kidney and liver function.A disrupted redox balance in cells also damages crucial biomolecules such as deoxyribonucleic acid(DNA),proteins and *** stress(OS)is elevated in diabetes mellitus and may be a major factor in the development and evolution of the typical long-term pathophysiology of diabetes and its associated complications[2].