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文献详情 >The Consistencies of Y‑Chromos... 收藏

The Consistencies of Y‑Chromosomal and Autosomal Continental Ancestry Varying among Haplogroups

作     者:Chuan-Chao Wang Lei Shang Hui‑Yuan Yeh Lan‑Hai Wei 

作者机构:Department of GeneticsHarvard Medical SchoolBostonMAUSA Department of ArchaeogeneticsMax Planck Institute for the Science of Human HistoryJenaGermany Key Laboratory of Forensic GeneticsInstitute of Forensic ScienceMinistry of Public SecurityBeijingChina School of Humanities and Social SciencesNanyang Technological UniversitySingapore State Key Laboratory of Genetic Engineering and Ministry of Education Key Laboratory of Contemporary AnthropologyCollaborative Innovation Center for Genetics and DevelopmentSchool of Life SciencesFudan UniversityShanghaiChina 

出 版 物:《Journal of Forensic Science and Medicine》 (法庭科学与法医学杂志(英文))

年 卷 期:2016年第2卷第4期

页      面:229-232页

学科分类:0710[理学-生物学] 0301[法学-法学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基  金:supported by the Max Planck Society and Harvard Medical School 

主  题:Ancestry inference autosomal single‑nucleotide polymorphism Y‑chromosome 

摘      要:The Y‑chromosome has been widely used in ancestry inference based on its region‑specific haplogroup ***,there is always a debate on how informative such a single marker is for inferring an individual’s genetic ***,we compared genetic ancestry inferences at continental level made by Y‑chromosomal haplogroups to those made by autosomal single‑nucleotide polymorphisms in 1230 samples of Affymetrix Human Origins *** highest ancestry proportions of a majority of individuals match the highest average continental‑ancestry proportions in haplogroups A,B,D,H,I,K,L,T,O,and *** high consistencies have not been observed in haplogroups E,C,G,J,N,Q,and R,but in some of their sublineages,such as E1a,E1b1a1,E1b1b1b1a,E2b1a,J1a2b,Q1a1a1,Q1a2a1a1,R1b1a2a1a,and *** the consistencies of Y‑chromosomal and autosomal continental ancestry vary among haplogroups,Y‑chromosome could provide valuable clues for individual’s continental ancestry.

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