Pd-Catalyzed 2,3-Allenylation of Oxindoles with 2,3-Allenylic Carbonates

作     者：Jie Lin Minqiang Jia Shengming Ma Jie Lin;Minqiang Jia;Shengming Ma

作者机构：Research Center for Molecular Recognition and SynthesisDepartment of ChemistryFudan University220 Handan LuShanghai200433 China State Key Laboratory of Organometallic ChemistryShanghaiInstitute of Organic ChemistryChinese Academy of Sciences345 Lingling LuShanghai200032 China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2021年第39卷第11期

页      面：3044-3050页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Financial support from the National Natural Science Founda tion Founda tion of China(Grant Nos.21690063 and 21988101)is greatly appreciated.We thank Mr.Yifan Cui in this group for reproducing the results of 3ba presented in Table 3 

主　　题：Palladium Allenes Chemoselectivity Allenylation Oxindoles 

摘      要：Allenes and oxindoles are two classes of very important compounds for medicinal chemistry and organic ***,it is of high interest to combine an allene and an oxindole into one ***,the first example of palladium-catalyzed exclusive 2,3-allenylation reaction of oxindoles with 2,3-allenylic carbonates has been successfully developed.A rationale for the selectivity of 2,3-allenylation over the expected 1,3-alkadienylation has been proposed.