Pd-Catalyzed 2,3-Allenylation of Oxindoles with 2,3-Allenylic Carbonates
作者机构:Research Center for Molecular Recognition and SynthesisDepartment of ChemistryFudan University220 Handan LuShanghai200433 China State Key Laboratory of Organometallic ChemistryShanghaiInstitute of Organic ChemistryChinese Academy of Sciences345 Lingling LuShanghai200032 China
出 版 物:《Chinese Journal of Chemistry》 (中国化学(英文版))
年 卷 期:2021年第39卷第11期
页 面:3044-3050页
核心收录:
学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
主 题:Palladium Allenes Chemoselectivity Allenylation Oxindoles
摘 要:Allenes and oxindoles are two classes of very important compounds for medicinal chemistry and organic ***,it is of high interest to combine an allene and an oxindole into one ***,the first example of palladium-catalyzed exclusive 2,3-allenylation reaction of oxindoles with 2,3-allenylic carbonates has been successfully developed.A rationale for the selectivity of 2,3-allenylation over the expected 1,3-alkadienylation has been proposed.