Epidemiology and Clinical Characteristics of the First 500 Positive Cases of COVID-19. A Multicenter Retrospective Study across the Najran Region of the Kingdom of Saudi Arabia (KSA)

作     者：Hadi J. Al Sulayyim Mohammed Ch Al-Noaemi Mohammed M. Alyami Shoab Ahmad Mohammad H. Alyami Hamad S. Alyami Ali D. Al-Swedan Ibraheem S. Banihameem Musallam A. Sedran Ali M. Al-Zubaidi Obaid M. Al Abbas Hadi J. Al Sulayyim;Mohammed Ch Al-Noaemi;Mohammed M. Alyami;Shoab Ahmad;Mohammad H. Alyami;Hamad S. Alyami;Ali D. Al-Swedan;Ibraheem S. Banihameem;Musallam A. Sedran;Ali M. Al-Zubaidi;Obaid M. Al Abbas

作者机构：General Directorate of Health Affairs Najran Ministry of Health Najran KSA Al-Ghad International College of Applied Medical Sciences Najran KSA Batterjee Medical College Jeddah KSA Najran University Najran KSA 

出 版 物：《Open Journal of Epidemiology》 (流行病学期刊（英文）)

年 卷 期：2021年第11卷第3期

页      面：222-236页

学科分类：0202[经济学-应用经济学] 02[经济学] 020205[经济学-产业经济学] 

主　　题：Epidemiology Characteristics COVID-19 Najran KSA 

摘      要：Introduction: Coronavirus Disease 2019 (COVID-19) is a viral infection that was first reported in Wuhan, China on 31 December 2019. This study aimed to clarify the epidemiology and clinical characteristics of 500 first COVID-19 in the Najran region, Saudi Arabia. Material and Methods: A multi-center retrospective study design was employed to study the first 500 confirmed COVID-19 positive cases in Najran province, Kingdom of Saudi Arabia (KSA). Data were collected from 1 March 2020 until 1 July 2020 and provided by the Infection Prevention and Control (IPC) department from the hospitals. Included cases were confirmed using real-time reverse transcriptase-polymerase chain reaction (RT-PCR). Demographic, vital signs, symptoms, incubation period, travel or exposure history medical history, and comorbidities were collected. Logistic regression analysis was used to explore the association between potential risk factors associated with symptoms occurrence of COVID-19. Results: The median age of 500 COVID-19 patients was 31 years;333 (66.6%) males. A total of 34 (6.8%) were Healthcare Workers (HCWs). Out of the 500 patients, 180 (36%) had at least one comorbid disease. The most common symptoms on admission were fever 281 (56.2%), cough 266 (53.2%), shortness of breath 166 (33.2%), and malaise 113 (22.6%). Most of the patients presented with mild disease severity 310 (62%). Nationality, age, and Diabetes Miletus (DM) were independently and significantly associated with being symptomatic (P β = 2.968, CI = 2.002 - 4.400, P = 0.0010). For every 1 year increase in age, the risk of being symptomatic increased by 5.8% (β = 1.045, CI = 1.033 - 1.058, P = 0.001). Compared with non-DM patients, DM patients had a 4.05 times higher risk (β = 4.05, CI = 2.188 - 7.507, P = 0.0