Persistence of Anti-SARS-CoV-2 IgM Antibody up to 8 Months Post-COVID-19

作     者：Carlos David A. Bichara Ednelza S. G. Amoras Gergiane L. Vaz Cléa N. C. Bichara Isabella P. C. Amaral Amaral Antonio C. R. Vallinoto Carlos David A. Bichara;Ednelza S. G. Amoras;Gergiane L. Vaz;Cléa N. C. Bichara;Isabella P. C. Amaral Amaral;Antonio C. R. Vallinoto

作者机构：Laboratório de Virologia Instituto de Ciências Biológicas Universidade Federal do Pará (UFPA) Belém Brasil Amaral Costa Medicina Diagnóstica Belém Brasil Faculdade de Medicina Centro de Ciências Biológicas e da Saúde Universidade do Estado do Pará (UEPA) Belém Brasil Programa de Pós-Graduaç ã o em Biologia de Agentes Infecciosos e Parasitários Instituto de Ciências Biológicas Universidade Federal do Pará (UFPA) Belém Brasil 

出 版 物：《Case Reports in Clinical Medicine》 (临床医学病理报告（英文）)

年 卷 期：2021年第10卷第9期

页      面：227-231页

学科分类：07[理学] 0701[理学-数学] 070101[理学-基础数学] 

主　　题：COVID-19 SARS-CoV-2 Antibodies IgM Persistence 

摘      要：Here, we present a longitudinal analysis of two patients who recovered from COVID-19 more than 8 months prior but showed persistent serological detection of anti-SARS-CoV-2 IgM. We still do not know the exact reason for this prolonged persistence of IgM in these patients. To our knowledge, these are the first reports of IgM persistence in the context of SARS-CoV-2 infection and point to the need for no longer using IgM as a diagnostic criterion for acute or recent COVID-19. One should opt for gold standard molecular methodologies due to their high sensitivity and specificity.