Infrared chemical imaging through non-degenerate two-photon absorption in silicon-based cameras
作者机构：Department of ChemistryUniversity of CaliforniaIrvineCA 92697USA Department of Biomedical EngineeringUniversity of CaliforniaIrvineCA 92697USA
出 版 物：《Light(Science & Applications)》 (光（科学与应用)（英文版）)
年 卷 期：2020年第9卷第1期
页 面：813-822页
核心收录：
学科分类：0808[工学-电气工程] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0803[工学-光学工程] 0702[理学-物理学]
基 金：funded by the National Institutes of Health R01GM132506.
主 题：absorption Infrared chemical
摘 要：Chemical imaging based on mid-infrared(MIR)spectroscopic contrast is an important technique with a myriad of applications,including biomedical imaging and environmental monitoring.Current MIR cameras,however,lack performance and are much less affordable than mature Si-based devices,which operate in the visible and nearinfrared regions.Here,we demonstrate fast MIR chemical imaging through non-degenerate two-photon absorption(NTA)in a standard Si-based charge-coupled device(CCD).We show that wide-field MIR images can be obtained at 100 ms exposure times using picosecond pulse energies of only a few femtojoules per pixel through NTA directly on the CCD chip.Because this on-chip approach does not rely on phase matching,it is alignment-free and does not necessitate complex postprocessing of the images.We emphasize the utility of this technique through chemically selective MIR imaging of polymers and biological samples,including MIR videos of moving targets,physical processes and live nematodes.
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