Joint Effects of Mexidol and Nitroglycerine on Nitric Oxide Formation in Animal Liver Tissues

作     者：Taasilkan Zhumabaeva Zoya Kuropteva Zhoomart Moldaliev Nazgul Zhumabaeva Amanai Kadyrbaeva Nurbek Bopoev Zhypargul Abdullaeva Taasilkan Zhumabaeva;Zoya Kuropteva;Zhoomart Moldaliev;Nazgul Zhumabaeva;Amanai Kadyrbaeva;Nurbek Bopoev;Zhypargul Abdullaeva

作者机构：Department of Natural Sciences Osh State University Osh Kyrgyzstan Institute of Biochemical Physics Russian Academy of Sciences Moscow Russia Department of Medicine Kyrgyz-Turkish University Manas Bishkek Kyrgyzstan Department of Hospital Therapy Zhalal-Abad State University Zhalal-Abad Kyrgyzstan International Hope School Bangladesh of Gulshan Branch Dhaka Bangladesh Science and Research Department Osh State University Osh Kyrgyzstan 

出 版 物：《American Journal of Molecular Biology》 (美国分子生物学期刊（英文）)

年 卷 期：2021年第11卷第3期

页      面：73-82页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：Nitroglycerine Liver Tissue Nitric Oxide Mexidol Joint Effect EPR Spectra 

摘      要：This work is investigating Mexidol (2-ethyl-6-methyl-3-hydroxy pyridine succinate) effect on the formation of nitric oxide (NO) in animal liver tissues, which is a regulator of many physiological processes and plays an important role in the vascular relaxation, neurotransmission and immune system functioning. Analyses performed by EPR spectroscopy revealed Hem-NO complex signals from paramagnetic centers in arbitrary units;produced nitrogen oxide amount in liver tissues was determined by method of double integration signals from nitrosyl complexes.