Probiotic Paenibacillus polymyxa 10 and Lactobacillus plantarum 16 enhance growth performance of broilers by improving the intestinal health

作     者：Baikui Wang Li Gong Yuanhao Zhou Li Tang Zihan Zeng Qi Wang Peng Zou Dongyou Yu Weifen Li Baikui Wang;Li Gong;Yuanhao Zhou;Li Tang;Zihan Zeng;Qi Wang;Peng Zou;Dongyou Yu;Weifen Li

作者机构：Key Laboratory of Molecular Animal Nutrition of the Ministry of EducationKey Laboratory of Animal Nutrition and Feed Science(Eastern of China)of the Ministry of AgricultureKey Laboratory of Animal Feed and Nutrition of Zhejiang ProvinceInstitute of Animal Nutrition and Feed SciencesCollege of Animal SciencesZhejiang University310058HangzhouChina Hainan InstituteZhejiang UniversitySanya 572000China 

出 版 物：《Animal Nutrition》 (动物营养（英文版）)

年 卷 期：2021年第7卷第3期

页      面：829-840页

核心收录：

学科分类：090502[农学-动物营养与饲料科学] 0905[农学-畜牧学] 09[农学] 

基　　金：supported by the Natural Science Foundation of Zhejiang Province(No.2014C32059 and No.2006C12086) the National High-Tech R&D Program Project(863)of China(No.2013AA102803D) 

主　　题：Paenibacillus polymyxa Lactobacillus plantarum Growth performance Intestinal health Broiler 

摘      要：With the ever-growing strict prohibitions on antibiotic growth promoters(AGP)in animal production,in-feed probiotics are becoming attractive alternatives to antibiotics in the poultry *** investigate the effects of Paenibacillus polymyxa 10 and Lactobacillus plantarum 16 on the growth performance and intestinal health of broilers,540 male Cobb 500 broilers of 1 d old were randomly divided into 3 groups with 6 replicates per group and 30 chicks per *** were fed with either a basal diet or basal diets supplemented with 1×108 colony-forming units(CFU)/kg *** 10(BSC10)or *** 16(Lac16)for 42 *** showed that Lac16 treatment improved(P0.05)the growth performance of the starter phase *** increased villus height(P0.05)at d 14,21 and 42 and villus height to crypt depth ratio(P0.05)at d 14 and 21 were observed in the ileum of the 2 probiotic ***,transmission electron microscopy results showed that the 2 probiotics enhanced the intestinal epithelial *** probiotic treatments up-regulated(P0.05)the mRNA expression of fatty acid binding protein 1(FABP1)and sodium-dependent glucose transporters-1(SGLT-1)in the ileal mucosa of broilers at d *** addition,BSC10 and Lac16 treatments significantly(P0.05)increased the relative abundance of short-chain fatty acids-producing bacteria,such as Butyricicoccus pullicaecorum,Faecalibacterium prausnitzii,Lachnospira and Cop-rococcu,and significantly(P0.05)decreased the relative abundance of enteric pathogens(Escherichia coli,Bacteroides fragilis and Shigella sonnei).Furthermore,the 2 probiotic treatments also increased the positive connection among the intestinal microbes and the carbohydrate metabolism-related pathways of the intes-tinal bacteria(P0.05),with decreasing(P0.05)nucleotides biosynthesis-related pathways of the intesti