SARS-CoV-2: Vaccines in the pandemic era

作     者：Dan-Dan Li Qi-Han Li Dan-Dan Li;Qi-Han Li

作者机构：Institute of Medical BiologyChinese Academy of Medicine Science&Peking Union Medical CollegeYunnan Key Laboratory of Vaccine Research and Development on Severe Infectious DiseasesNo.935 Jiaoling RoadKunming 650118YunnanChina 

出 版 物：《Military Medical Research》 (军事医学研究（英文版）)

年 卷 期：2021年第8卷第2期

页      面：238-252页

核心收录：

学科分类：1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学] 

基　　金：supported by the National Key R&D Program of China(2020YFC0849700) the Program of Chinese Academy of Medicine Science the Major Science and Technology Special Projects of Yunnan Province。 

主　　题：Severe acute respiratory syndrome coronavirus 2 Coronavirus disease 2019 Vaccine Vaccine candidate Clinical trials 

摘      要：Coronavirus disease 2019(COVID-19),caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has caused millions of infections and deaths worldwide since its emergence in December 2019.As there is little or no natural immunity in the human population or specific anti-COVID-19 drugs,researchers from the government,academia and industry are developing vaccines at an unprecedented speed to halt the pandemic.In this review,the results of animal experiments and clinical trials on several vaccine technical platforms are summarized,and several challenges are also discussed to further promote the development,evaluation and application of vaccines during the challenging situation of the global pandemic.