Feasibility of Subtraction Coronary Computed Tomographic Angiography and Influencing Factor Analysis: a Retrospective Study

作     者：Chao HUANG Wei-jia WAN Yu-huan YAO Li-ming XIA Wen-hua HUANG Chao HUANG;Wei-iia WAN;Yu-huan YAO;Li-ming XIA;Wen-hua HUANG

作者机构：Department of RadiologyTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China 

出 版 物：《Current Medical Science》 (当代医学科学（英文）)

年 卷 期：2021年第41卷第4期

页      面：821-826页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by Hubei Health Committee of China(No.WJ2019M119) 

主　　题：coronary computed tomographic angiography calcification artifacts coronary subtraction diagnosis accuracy influencing factors 

摘      要：Objective To investigate the feasibility of subtraction coronary computed tomographic(CT)angiography(SubCCTA)to decline calcium artifacts and improve diagnostic accuracy in the presence of coronary calcification and analyze the factors that influence *** A total of 294 patients suspected of having coronary artery diseases underwent coronary computed tomographic angiography(CCTA)and *** stenoses were blindly evaluated by two experienced radiologists,which were compared with invasive coronary angiography(ICA).Multiple statistical indexes were adopted to analyze the value of SubCCTA for the diagnosis of calcium *** The diagnosable rate of SubCCTA was 67.2%(n=197),and the non-diagnosable rate was 32.8%(n=97).Using SubCCTA,the false positive rate decreased from 56.5%to 17.4%,and the corresponding diagnostic accuracy was increased from 83.6%to 92.9%.Univariate logistic regression analysis showed that height(OR=1.029,95%CI=1.001–1.058),weight(OR=1.025,95%CI=1.004–1.046),left ventricular size(OR=1.018,95%CI=1.007–1.030),cardiothoracic ratio(OR=39.917,95%CI=1.244–1281.098),the average heart rate(OR=0.866,95%CI=0.836–0.896)and heart rate range(OR=0.882,95%CI=0.853–0.912)might be the factors influencing *** This study suggested that SubCCTA could help improve diagnostic accuracy in the presence of calcium ***,several factors were discovered for the first time to possibly influence SubCCTA,which will be helpful in improving the subtracted image quality.