Bacterial co-infection in patients with SARS-CoV-2 in the Kingdom of Bahrain
作者机构：Medical Microbiology SectionPathology DepartmentSalmaniya Medical ComplexManama 00000Bahrain Microbiology DepartmentRoyal College of Surgeons in Ireland-BahrainManama 00000Bahrain Infection Disease UnitDepartment of Internal MedicineSalmaniya Medical ComplexMinistry of HealthKingdom of BahrainManama 00000Bahrain Department of Infectious DiseaseArabian Gulf UniversityManama 00000Bahrain Department of PediatricsUniversity Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 00000Bahrain Department of PediatricsFaculty of MedicineTanta UniversityTanta 000000Al GharbiaEgypt
出 版 物：《World Journal of Virology》 (世界病毒学杂志)
年 卷 期：2021年第10卷第4期
页 面：168-181页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：COVID-19 Bacterial co-infection Fungi Hospital-acquired infection Kingdom of Bahrain
摘 要：BACKGROUND The coronavirus disease 2019(COVID-19)pandemic presents a significant challenge to the medical profession,increasing in the presence of microbial *** and Fungal co-infections increase the risk of morbidity and mortality in patients with *** To study the bacterial profile in patients with COVID-19 who needed admission to receive treatment in the main centres concerned with managing COVID-19 disease in the Kingdom of *** The study was a retrospective observational analysis of the bacterial profile and the bacterial resistance in patients with confirmed COVID-19 disease who needed admission to receive treatment in the main centres assigned to manage patients with COVID-19 disease in the Kingdom of Bahrain from February to October *** used the electronic patients’records and the microbiology laboratory data to identify patients’demographics,clinical data,microbial profile,hospital or community-acquired,and the *** The study included 1380 patients admitted with confirmed COVID-19 disease during the study period.51%were admitted from February to June,and 49%were admitted from July to October 2020,with a recurrence rate was 0.36%.There was a significant increase in bacterial and fungal co-infection in the second period compared to the first *** most common isolated organisms were the gram-negative bacteria(mainly Klebsiella pneumoniae,Pseudomonas aeruginosa,multi-drug resistant Acinetobacter baumannii,and Escherichia coli),the grampositive bacteria(mainly coagulase negative Staphylococci,Enterococcus faecium,Enterococcus faecalis,Staphylococcus aureus)and fungaemia(Candida galabrata,Candida tropicalis,Candida albicans,Aspergillus fumigatus,Candida parapsilosis,Aspergillus niger).The hospital-acquired infection formed 73.8%,61.6%,100%gram-negative,gram-positive and *** of the hospital-acquired infection occurred in the second period with a higher death rate than communityacquired infections
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