Immunologic mechanism of fungal keratitis
作者机构：Tianjin Key Laboratory of Retinal Functions and DiseasesTianjin Branch of National Clinical Research Center for Ocular DiseaseEye Institute and School of OptometryTianjin Medical University Eye HospitalTianjin 300384China
出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)
年 卷 期：2021年第14卷第7期
页 面：1100-1106页
核心收录：
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
基 金：Supported by the Natural Science Foundation of Tianjin(No.19JCYBJC25700) Clinical Key Discipline(Specialty)Construction Project of Tianjin(No.TJLCZDXKM002) Science and Technology Projects of Social Development of Tianjin Binhai New District(No.BHXQKJXM-SF-2018-05) Science and Technology Projects of Health Commission of Tianjin Binhai New District(No.2019BWKZ008)
主 题：fungal keratitis innate immunity adaptive immunity pattern recognition receptors immune cells
摘 要：Fungal keratitis(FK)is a refractory disease that poses a serious threat to vision,with common risk factors like eye trauma,contact lens wearing,topical corticosteroids and antibiotic ***,topical and systemic anti-fungal drugs and ocular surgeries are still the main therapeutic ***,the pathogenesis of FK,especially the immunologic mechanism within it,has not yet been deeply clarified.A better understanding of the pathogenesis of FK is imperative for more effective therapies and ***,the immune protection strategies are also urgently required to manage *** review highlights recent advances in the immunologic mechanism in the pathogenesis of FK,in hope of providing valuable reference information for more effective anti-fungal treatment.
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