“Pulmonary target sign” as a diagnostic feature in chest computed tomography of COVID-19

作     者：Ramezan Jafari Nematollah Jonaidi-Jafari Houshyar Maghsoudi Fatemeh Dehghanpoor U Joseph Schoepf Kyle A Ulversoy Amin Saburi 

作者机构：Department of RadiologyFaculty of MedicineBaqiyatallah University of Medical SciencesTehran 11151877Iran Health Research CenterBaqiyatallah University of Medical SciencesTehran 11151877Iran Department of Radiology and Radiological ScienceMedical University of South CarolinaCharlestonSC 29425United States Faculty of MedicineAugusta University/University of Georgia Medical PartnershipAthensGA 30606United States Chemical Injuries Research CenterSystems Biology and Poisonings InstituteBaqiyatallah University of Medical SciencesTehran 11151877Iran 

出 版 物：《World Journal of Radiology》 (世界放射学杂志（英文版）（电子版）)

年 卷 期：2021年第13卷第7期

页      面：233-242页

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Bayer Bracco ElucidBioImagingGuerbet Heart Flow, Inc Keya Medical Siemens Healthineers 

主　　题：Chest computed tomography Diagnosis Viral pneumonia COVID-19 Pulmonary target sign Case report 

摘      要：BACKGROUND In chest computed tomography(CT)scan,bilateral peripheral multifocal groundglass opacities,linear opacities,reversed halo sign,and crazy-paving pattern are suggestive for coronavirus disease 2019(COVID-19)in clinically suspicious cases,but they are not specific for the diagnosis,as other viral pneumonias,like influenza and some viral pneumonia may show similar imaging *** To find a specific imaging feature of the disease would be a welcome guide in diagnosis and management of challenging *** Chest CT imaging findings of 650 patients admitted to a university Hospital in Tehran,Iran between January 2020 and July 2020 with confirmed COVID-19 infection by RT-PCR were reviewed by two expert *** addition to common non-specific imaging findings of COVID-19 pneumonia,radiologic characteristics of“pulmonary target sign(PTS)were *** is defined as a circular appearance of non-involved pulmonary parenchyma,which encompass a central hyperdense dot surrounded by ground-glass or alveolar *** PTS were presented in 32 cases(frequency 4.9%).The location of the lesions in 31 of the 32 cases(96.8%)was peripheral,while 4 of the 31 cases had lesions both peripherally and *** 25 cases,the lesions were located near the pleural surface and considered pleural based and half of the lesions(at least one lesion)were in the lower segments and lobes of the lungs.22 cases had multiple lesions with a68%*** than 87%of cases had an adjacent bronchovascular ***-glass opacities were detectable adjacent or close to the lesions in 30 cases(93%)and only in 7 cases(21%)was consolidation adjacent to the *** Although it is not frequent in COVID-19,familiarity with this feature may help radiologists and physicians distinguish the disease from other viral and noninfectious pneumonias in challenging cases.