The Alkaloids from Leaves of Croton hemiargyerius var. gymnodiscus
巴豆属植物Croton hemiargyerius ***中生物碱的研究(英文)作者机构：北京大学天然药物及仿生药物国家重点实验室北京100083 里约联邦大学天然产物研究中心
出 版 物：《Journal of Chinese Pharmaceutical Sciences》 (中国药学（英文版）)
年 卷 期：2003年第12卷第3期
页 面：117-122页
学科分类：1007[医学-药学(可授医学、理学学位)] 100701[医学-药物化学] 10[医学]
主 题：csroton hemiargyerius new alkaloids hemiargines A, B, C, D
摘 要：Aim Investigation of alkaloids from the leaves of Brazilian medicinal plantCroton hemiargyerius var. gymnodiscus. Methods Silica gel column chromatography was used repeatedlyfor the isolation and purification, and their structures were identified by extensive spectroscopyand comparison of the chemical and physical data with those of authentic samples reported inliterature. Results Twelve alkaloids were isolated and their structures were identified. ConclusionFour new alkaloids named hemiargines A (1), B (5), C (6) and D (7), together with eight knownalkaloids namely isoc-orydine (2), corydine (3), norcorydine (4), salutaridine (8), glaucine (9),tetrahydropalmatrubine (10), xylopinoine (11), and norlaudanosine (12) were isolated.
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