Rh同种免疫妇女的妊娠结局
Pregnancy outcome for Rh-alloimmunized women作者机构：Av. Lopes de Azevedo 888 S.ao Paulo SP 05603- 001 Brazil
出 版 物：《世界核心医学期刊文摘（妇产科学分册）》 (Core Journal in Obstetrics/Gynecology)
年 卷 期：2005年第1卷第12期
页 面：59-60页
学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学]
主 题：Rh同种免疫 妊娠结局 围生儿死亡率 大脑中动脉 分光光度法 血细胞比容 观察性研究 多普勒超声检查 水分析
摘 要：Objective: To compare perinatal results of Rh-alloimmunized pregnancies managed with spectrophotometric amniotic fluid analysis or fetal middle cerebral artery Doppler ultrasonographic velocimetry. Method: A descriptive observational study involving 291 consecutive Rh- negative pregnancies. Group 1 consisted of 74 isoimmunized women managed with amniotic fluid spectrophotometry; group 2 of 25 isoimmunized women managed with Doppler ultrasonography; and group 3 of 192 nonimmunized Rh-negative women. The variables analyzed were need for intrauterine or neonatal transfusion, mode and time of delivery, birth weight, neonatal hematocrit, and perinatal mortality. Results: Need for intrauterine transfusion, birth weight, prematurity, rate of cesarean section, and perinatal mortality were similar in groups 1 and 2. Neonatal hematocrit was significantly lower and the need for neonatal transfusion was significantly higher when spectrophotometry rather than Doppler ultrasonographic velocimetry was used. Conclusion: Fetuses managed with Doppler ultrasonographic velocimetry had a higher hematocrit at birth and a lesser need for neonatal transfusion, suggesting that this noninvasive method of monitoring fetal anemia is a better choice.
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