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The Chemistry and Biological Activities of Natural Products from Northern African Plant Families:From Taccaceae to Zygophyllaceae

作     者:Fidele Ntie-Kang Leonel E.Njume Yvette I.Malange Stefan Gunther Wolfgang Sippl Joseph N.Yong 

作者机构:Department of Pharmaceutical ChemistryMartin-Luther University of Halle-WittenbergWolfgang-Langenbeck-Str.406120 Halle(Saale)Germany Department of ChemistryFaculty of ScienceUniversity of BueaP.O.Box 63BueaCameroon Department of ChemistryFaculty of ScienceChemical and Bioactivity Information CentreUniversity of BueaP.O.Box 63BueaCameroon Institute of Pharmaceutical SciencesResearch Group Pharmaceutical BioinformaticsAlbert-Ludwigs-Universitat FreiburgHermann-Herder-Strasse 979104 FreiburgGermany 

出 版 物:《Natural Products and Bioprospecting》 (应用天然产物(英文))

年 卷 期:2016年第6卷第2期

页      面:63-96页

学科分类:0710[理学-生物学] 0832[工学-食品科学与工程(可授工学、农学学位)] 1007[医学-药学(可授医学、理学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 07[理学] 1001[医学-基础医学(可授医学、理学学位)] 070303[理学-有机化学] 0703[理学-化学] 0901[农学-作物学] 0902[农学-园艺学] 

基  金:Financial support is acknowledged from Lhasa Ltd,Leeds,UK through the Chemical and Bioactivity Information Centre(CBIC),University of Buea,Cameroon FNK acknowledges a Georg Forster fellowship for postdoctoral researchers from the Alexander von Humboldt Foundation,Germany. 

主  题:Africanflora Biologicalactivities Ethnobotany Naturalproducts Traditionalmedicine 

摘      要:Traditional medicinal practices have a profound influence on the daily lives of people living in developing countries,particularly in Africa,since the populations cannot generally afford the cost of Western medicines.We have undertaken to investigate the correlation between the uses of plants in Traditional African medicine and the biological activities of the derived natural products,with the aim to validate the use of traditional medicine in Northern African communities.The literature is covered for the period 1959-2015 and part III of this review series focuses on plant families with names beginning with letters T to Z.The authors have focused on curating data from journals in natural products and phytomedicine.Within each journal home page,a query search based on country name was conducted.All articles‘‘hits’’were then verified,one at a time,that the species was harvested within the Northern African geographical regions.The current data partly constitutes the bases for the development of the Northern African natural compounds database.The review discusses 284 plant-based natural compounds from 34 species and 11 families.It was observed that the ethnobotanical uses of less than 40%of the plant species surveyed correlated with the bioactivities of compounds identified.

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