RHBDF1 promotes AP-1-activated endothelial-mesenchymal transition in tumor fibrotic stroma formation
作者机构:State Key Laboratory of Medicinal Chemical BiologyCollege of PharmacyTianjin Key Laboratory of Molecular Drug ResearchNankai UniversityTianjinChina State Key Laboratory of Elemento-Organic Chemistry and Department of Chemical BiologyNational Pesticide Engineering Research Center(Tianjin)Collaborative Innovation Center of Chemical Science and Engineering(Tianjin)College of ChemistryNankai UniversityTianjinChina
出 版 物:《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗(英文))
年 卷 期:2021年第6卷第8期
页 面:2307-2310页
核心收录:
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金:We are grateful for the funding provided by grants from the National Natural Science Foundation of China(NSFC)projects(Grant nos.81972687 82073064 and 81874167)
主 题:tumor transition hypoxic
摘 要:Dear Editor,There is a growing body of evidence that the human rhomboid family-1 gene(RHBDF1)plays an important role in the modulation of tumor inflammatory(Supplementary ***)and hypoxic microenvironment.