Rh(Ⅲ)-Catalyzed Diverse C-H Functionalization of Iminopyridinium Ylides

作     者：Zhenzhen Dong Pengfei Li Xingwei Li Bingxian Liu Zhenzhen Dong;Pengfei Li;Xingwei Li;Bingxian Liu

作者机构：NMPA Key Laboratory for Research and Evaluation of Innovative DrugCollaborative Innovation Center of Henan Province for Green Manufacturing of Fine ChemicalsSchool of Chemistry and Chemical EngineeringHenan Normal UniversityXinxiangHenan 453007China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2021年第39卷第9期

页      面：2489-2494页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：The NSFC(Nos.21801066,2152520&U1804283 and 21801067) the Central Plains Scholars and Scientists Studio Fund(2018002) China Postdoctoral Science Foundation(2020M682307)are acknowledged.We also thank the financial support from Henan Key Laboratory of Organic Functional Molecules and Drug Innovation 

主　　题：C-H functionalization Iminopyridinium ylide Diverse transformation Redox-neutral Ylidic directing group 

摘      要：Divergent synthesis of useful skeletons has been realized via rhodium(Ⅲ)-catalyzed C-H activation of iminopyridinium ylides and coupling with various unsaturated coupling *** and isoquinolones were obtained via cleavage of the C-N or N-N bond in the ylidic di recti ng group,while fluorinated alkenes were delivered with the di recti ng group in *** reactions occurred with wide substrate scopes and good efficiency under redox-neutral and air-tolerant *** products exhibit solid-state fluoresce nt property and bioactivity of in hibiti on toward huma n cancer cells.