Off-hour effect is not significant in endovascular treatment for anterior circulation large vessel occlusion in a multicentre registry

作     者：Mingming Zha Qingwen Yang Shuo Liu Kangmo Huang Xiaohao Zhang Min Wu Haodi Cai Qiushi Lv Rui Liu Dong Yang Xinfeng Liu 

作者机构：Department of NeurologySoutheast UniversityNanjingJiangsuChina Department of Internal MedicineSoutheast UniversityNanjingJiangsuChina Department of NeurologyMedical School of Nanjing UniversityNanjingJiangsuChina Department of NeurologySouthern Medical UniversityGuangzhouGuangdongChina Department of NeurologyNanjing Jinling HospitalNanjingJiangsuChina 

出 版 物：《Stroke & Vascular Neurology》 (卒中与血管神经病学（英文）)

年 卷 期：2021年第6卷第4期

页      面：640-648,I0093页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：This study was partly supported by the National Nature and Science Foundation(Grant No.81901218 81870946 81530038 and 81701299) 

主　　题：centre treatment effect 

摘      要：Background and purpose Whether the off-hour effect has an impact on workflow and outcomes of endovascular treatment(EVT)for anterior circulation large vessel occlusion(AC-LVO)remains *** study aimed to compare the characteristics and outcomes of patients who presented or were treated during off-hour versus on-hour in a multi-center *** AC-LVO patients from 21 centres were categorised into the off-hour group and the on-hour ***-hour(weekends,holidays,and 18:00-7:59 on weekdays)and on-hour(8:00-17:59 on weekdays except for holidays)were defined according to arrival and groin-puncture time points,*** comparisons between patients both arrived and treated during off-hour(true off-hour)and on-hour(true on-hour)were *** primary outcome was the 90-day modified Rankin Scale(mRS)*** outcomes included favourable outcome(mRS 0-2 at 90 days),EVT-related time metrics,and other clinical *** and binary logistic regression and linear regression were taken to adjust for confounding *** Of all 698 patients enrolled,435(62.3%)and 456(65.3%)patients were categorised into the off-hour arrival and off-hour puncture group,*** onset to door time(adjustedßcoefficient:−21.56;95%CI−39.96 to−3.16;p=0.022)was noted in the off-hour arrival *** and dichotomous mRS scores at 90 days were comparable between the off-hour group and the on-hour group regardless of off-hour *** time metrics and outcomes were comparable between the two *** 595 patients both presented and were treated during off-hour or on-hour,394 patients were categorised into the true off-hour group and 201 into the true on-hour *** metrics and clinical outcomes were similar between the true off-hour and the true on-hour *** The off-hour effect was not significant regarding clinical outcomes and in-hospital workflow in AC-LVO patients receiving EVT in this Chinese multicentr