New Insights from Chemical Biology:Molecular Basis of Transmission,Diagnosis,and Therapy of SARS-CoV-2

作     者：Zilong Zhao Yaling Wang Liping Qiu Ting Fu Yu Yang Ruizi Peng Mengyu Guo Lichun Mao Chunying Chen Yuliang Zhao Weihong Tan 

作者机构：Molecular Science and Biomedicine Laboratory(MBL)State Key Laboratory of Chemo/Bio-Sensing and ChemometricsCollege of Chemistry and Chemical EngineeringCollege of BiologyHunan UniversityChangsha 410082 CAS Key Laboratory for Biomedical Effects of Nanomaterials and NanosafetyCAS Center for Excellence in NanoscienceNational Center for Nanoscience and Technology of ChinaBeijing 100190 The Cancer Hospital of the University of Chinese Academy of SciencesInstitute of Cancer and Basic Medicine(IBMC)Chinese Academy of SciencesZhejiang 310022 Institute of Molecular Medicine(IMM)Renji HospitalState Key Laboratory of Oncogenes and Related GenesShanghai Jiao Tong University School of MedicineCollege of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240 University of Chinese Academy of SciencesBeijing 100049 GBA Research Innovation Institute for NanotechnologyGuangdong 510700 

出 版 物：《CCS Chemistry》 (中国化学会会刊（英文）)

年 卷 期：2021年第3卷第1期

页      面：1501-1528页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 0703[理学-化学] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：This research was made possible as a result of a generous grant from the National Key Research Program(no.2020YFC0842800) the Science and Technology Project of Hunan Province(no.2020SK3008) the Ministry of Science and Technology of China(nos.2016YFA0201600 and 2018YFE0117200) 

主　　题：SARS-CoV-2 COVID-19 transmission diagnosis therapy 

摘      要：Coronavirus disease 2019(COVID-19)is caused by a novel strain of coronavirus,designated as severe acute respiratory syndrome coronavirus 2(SARSCoV-2).It has caused a global pandemic rapidly sweeping across all countries,bringing social and economic hardship to *** countries have implemented early warning measures to detect,isolate,and treat patients infected with *** minireview summarizes some of those steps,in particular,testing methods and drug development in the context of chemical biology,and discusses the molecular basis of COVID-19’s virulent transmissibility.