Enrichment of the less polar ginsenoside (Rg3) from ginseng grown in New Zealand by post-harvest processing and extraction
作者机构：School of Food and Advanced TechnologyMassey UniversityPalmerston North 4442New Zealand Riddet InstituteMassey UniversityPalmerston North 4442New Zealand
出 版 物：《Traditional Medicine Research》 (TMR传统医学研究)
年 卷 期：2021年第6卷第4期
页 面：136-149页
学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
基 金：Alpha-Massey Natural Nutraceuticals Research Centre
主 题：New Zealand grown ginseng Less polar ginsenoside Ginsenoside Rg3 Ginsenoside transformation
摘 要：Background:Previous studies showed that New Zealand-grown ginseng contains an abundance of ginsenosides and that rare less polar ginsenosides,such as Rg3,exhibit more pharmacological activities than polar ginsenosides,which are the major components of ***:The ginsenoside profile of New Zealand-grown Panax ginseng was manipulated by treatment with acetic acid,sodium hydroxide,pH,and high *** abundance of 23 ginsenosides extracted by different treatments was quantified using high-performance liquid ***:Treatment with 0.5 mol/L acetic acid can stimulate the degradation of polar ginsenosides to less polar ginsenosides(5.6%Rg3 was accumulated,P0.0001).Furthermore,when ginseng root was treated at 121℃ for 100 min in a pH 3.0 acetic acid aqueous solution,the majority of the polar ginsenosides were converted into less polar ***,83.46±3.69%(P=0.0360)of the less polar ginsenosides and 41.01±2.39%(P=0.0412)of Rg3 were *** contrast,alkali treatment did not convert the polar ginsenosides into less polar ginsenosides at mild temperature and less conversion was observed compared with acid treatment at high ***:This is the first attempt to manipulate the ginsenoside profile of New Zealand-grown *** conditions(high temperature with low pH)may be modified to produce and enrich the less polar ginsenoside fraction(especially Rg3)from the total ginseng extract.
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