The blue light receptor CRY1 interacts with GID1 and DELLA proteins to repress GA signaling during photomorphogenesis in Arabidopsis

作     者：Ming Zhong Bingjie Zeng Dongying Tang Jiaxin Yang Lina Qu Jindong Yan Xiaochuan Wang Xin Li Xuanming Liu Xiaoying Zhao Ming Zhong;Bingjie Zeng;Dongying Tang;Jiaxin Yang;Lina Qu;Jindong Yan;Xiaochuan Wang;Xin Li;Xuanming Liu;Xiaoying Zhao

作者机构：College of BiologyHunan Province Key Laboratory of Plant Functional Genomics and Developmental RegulationHunan Hybrid Rape Engineering and Technology Research CenterHunan UniversityChangsha 410082China Shenzhen InstituteHunan UniversityShenzhen 518057China 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2021年第14卷第8期

页      面：1328-1342页

核心收录：

学科分类：0710[理学-生物学] 071001[理学-植物学] 07[理学] 

基　　金：supported by the National Natural Science Foundation of China(no.31171176) the Natural Science Foundation of Hunan Province(no.2020JJ4183) the Basic Research Program of Changsha Municipal Science and Technology(no.kq1901028) 

主　　题：cryptochrome 1 blue light gibberellic acid GID1 DELLA proteins 

摘      要：Light is a critical environmental cue that regulates a variety of diverse plant developmental *** 1(CRY1)is the major photoreceptor that mediates blue light-dependent photomorphogenic responses such as the inhibition of hypocotyl ***(GA)participates in the repression of photomorphogenesis and promotes hypocotyl ***,the antagonistic interaction between blue light and GA is not well ***,we report that blue light represses GA-induced degradation of the DELLA proteins(DELLAs),which are key negative regulators in the GA signaling pathway,via CRY1,thereby inhibiting the GA response during hypocotyl *** in vitro and in vivo biochemical analyses demonstrated that CRY1 physically interacts with GA receptors-GA-INSENSITIVE DWARF 1 proteins(GID1s)-and DELLAs in a blue light-dependent ***,we showed that CRY1 inhibits the association between GID1s and ***,CRY1 antagonizes the function of GID1s to repress the expression of cell elongation-related genes and thus hypocotyl *** together,our findings demonstrate that CRY1 coordinates blue light and GA signali ng for plant photomorphogenesis by stabilizing DELLAs through the binding and in activation of GID1s,providing new in sights into the mechanism by which blue light antagonizes the function of GA in photomorphogenesis.