Influencing Factors for Erectile Dysfunction of Young Adults with No Response to PDE5i
作者机构：Department of UrologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China
出 版 物：《Current Medical Science》 (当代医学科学（英文）)
年 卷 期：2021年第41卷第3期
页 面：529-534页
核心收录：
学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题：erectile dysfunction PDE5 inhibitors influencing factor
摘 要：Erectile dysfunction(ED)is a common male *** orally-administered phosphodiesterase type 5 inhibitors(PDE5 inhibitors)are now recognized as the primary pharmacological treatment method for ED,20%-30%of the patients treated with PDE5 inhibitors exhibit no significant *** study aims to investigate the influencing factors of ED in young adults with no response to PDE5 *** patients who would take PDE5 inhibitors were included and investigated with a *** with no response to PDE5 inhibitors(tadalafil and sildenafil)served as study group,and those with response to PDE5 inhibitors as control *** Chi square test and logistic regression analysis were applied to find the potential influencing *** total,378 ED patients were ***-three(24.6%)cases were non-responsive to PDE5 inhibitors,and the remaining 285(75.4%)responded to PDE5 *** multiple logistic regression analysis,we found that history of drinking(OR=3.152;95%CI 1.672-6.975),spousal noncooperation(OR=2.994;95%CI 1.589-5.638),number of fixed sex partners(OR=0.358;95%CI 0.132-0.651),duration of ED(OR=3.356;95%CI 1.352-8.333),and depression(OR=3.689;95%CI 1.579-8.979)could be the influencing factors for ED patients’non-response to PDE5 *** conclusion,history of drinking,spousal noncooperation,number of fixed sex partner,long duration of ED,and depression could be the influencing factors for ED patients non-response to PDE5 *** and doctors should pay attention to these factors.
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