Exosome-Coated Zeolitic Imidazolate Framework Nanoparticles for Intracellular Detection of ATP

作     者：Wenxing Lv Ziwei Han Yike Li Yanjuan Huang Jiashu Sun Xiaoquan Lu Chao Liu Wenxing Lv;Ziwei Han;Yike Li;Yanjuan Huang;Jiashu Sun;Xiaoquan Lu;Chao Liu

作者机构：Tianjin Key Laboratory of Molecular Optoelectronic SciencesDepartment of ChemistrySchool of ScienceTianjin UniversityTianjin 300072China Beijing Engineering Research Center for BioNanotechnologyCAS Key Laboratory of Standardization and Measurement for NanotechnologyCAS Center for Excellence in NanoscienceNational Center for Nanoscience and TechnologyBeijing 100190China School of Future TechnologyUniversity of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Bioelectrochemistry and Environmental Analysis of Gansu ProvinceCollege of Chemistry and Chemical EngineeringNorthwest Normal UniversityLanzhouGansu 730070China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2021年第39卷第8期

页      面：2107-2112页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：This work was supported financially by the National Natural Science Foundation of China(Nos.22025402,91959101,and 21904028) Chinese Academy of Sciences(Nos.YJKYYQ20190068 and ZDBS-LY-SLH025) the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000) 

主　　题：ATP Exosome Metal-organic frameworks Microreactors Nan oparticles 

摘      要：The intracellular delivery of metal-organic frameworks(MOFs)encapsulated with functional biomolecules represents a promising av-enue in the field of biomedicine and *** improve the cellular uptake efficiency of MOFs,here we report the fabrication of cancer cell-derived exosome membra ne(EM)-coated zeolitic imidazolate framework-8(EM-ZIF-8)nan oparticles by using a microfluidic son ication device.