Pulmonary alveolar proteinosis complicated with tuberculosis:A case report
作者机构：Department of Laboratory MedicineWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Respiratory and Critical Care MedicineWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2021年第9卷第17期
页 面：4400-4407页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金：the National Science and Technology Major Project of the Ministry of Science and Technology of China No.2018ZX10715-003
主 题：Pulmonary alveolar proteinosis Pulmonary tuberculosis Bronchoalveolar lavage Case report
摘 要：BACKGROUND Pulmonary alveolar proteinosis(PAP)is a rare lung disease characterized by the accumulation of phospholipoproteinaceous material in the *** of PAP complicated with tuberculosis are much more complex and have rarely been well *** SUMMARY We describe a 21-year-old Han Chinese patient with suspicious lung infection associated with mild restrictive ventilatory dysfunction and diffusion *** resolution computed tomography revealed a“crazy-pavingappearance and multiple pulmonary miliary nodules around the *** lavage demonstrated a small amount of periodic acid-Schiff positive proteinaceous materials.A serological test for the presence of a Mycobacterium tuberculosis antibody and an interferon-gamma release assay were both *** patient received a standard course of first-line anti-tuberculosis treatment after diagnostic bronchoalveolar *** date,clinical remission has been achieved and maintained for five *** In summary,the diagnosis of PAP complicated with tuberculosis was supported by a combination of clinical manifestations,imaging,pulmonary function,laboratory examinations,bronchoalveolar lavage,*** case highlighted that diagnostic bronchoalveolar lavage in combination with anti-tuberculosis treatment is a safe and effective option for mild PAP patients with tuberculosis.
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