Comparison of white-light endoscopy,optical-enhanced and aceticacid magnifying endoscopy for detecting gastric intestinal metaplasia:A randomized trial

作     者：Ying-Hao Song Li-Dong Xu Meng-Xuan Xing Kun-Kun Li Xing-Guo Xiao Yong Zhang Lu Li Yan-Jing Xiao Yu-Lei Qu Hui-Li Wu 

作者机构：Xinxiang Medical UniversityXinxiang 453000Henan ProvinceChina Department of GastroenterologyZhengzhou Central Hospital Affiliated to Zhengzhou UniversityZhengzhou 450000Henan ProvinceChina Department of PathologyZhengzhou Central Hospital Affiliated to Zhengzhou UniversityZhengzhou 450000Henan ProvinceChina Department of GastroenterologyPeople's Hospital of Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2021年第9卷第16期

页      面：3895-3907页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Key Project of Science and Technology of Henan No.202102310382 

主　　题：Magnifying endoscopy Optical-enhanced Acetic-acid Gastric intestinal metaplasia 

摘      要：BACKGROUND Gastric intestinal metaplasia(GIM)is a precancerous lesion of the stomach,which severely affects human life and ***,a variety of endoscopic techniques are used to screen/evaluate *** white-light endoscopy(WLE)and acetic-acid chromoendoscopy combined with magnifying endoscopy(MEAAC)are the interventions of choice due to their diagnostic efficacy for ***-enhanced magnifying endoscopy(ME-OE)is a new virtual chromoendoscopy technique to identify GIM,which combines bandwidth-limited light and image enhancement processing technology to enhance the detection of mucosal and vascular *** hypothesized that ME-OE is superior to WLE and MEAAC in the evaluation of *** To directly compare the diagnostic value of WLE,ME-AAC,and ME-OE for detection of *** A total of 156 patients were subjected to consecutive upper gastrointestinal endoscopy examinations using WLE,ME-AAC,and *** findings were utilized as the reference ***,sensitivity,specificity,and positive and negative predictive values of the three endoscopy methods in the diagnosis of GIM were ***,the time to diagnosis with MEAAC and ME-OE was *** experts and two non-experts evaluated the GIM images diagnosed using ME-OE,and diagnostic accuracy and intra-and inter-observer agreement were *** GIM was detected in 68 of 156 patients(43.6%).The accuracy of ME-OE was highest(91.7%),followed by ME-AAC(86.5%),while that of WLE(51.9%)was ***-site analysis showed that the overall diagnostic accuracy of ME-OE was higher than that of ME-AAC(P=0.011)and WLE(P0.001).The average diagnosis time was lower in ME-OE than in ME-AAC(64±7 s vs 151±30 s,P0.001).Finally,the inter-observer agreement was strong for both experts(k=0.862)and non-experts(k=0.800).The internal consistency was strong for experts(k=0.713,k=0.724)and moderate for non-experts(k=0.667,k=0.598).CONCLUSION For endoscopists,especially experi